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References
Avise J . Phylogeography: the history and formation of species Harvard University Press, Cambridge, MA 2000
Howell N . Human mitochondrial disease: answering questions and questioning answers Int Rev Cytol 1997 186: 49–116
Awadalla P, Eyre-Walker A, Maynard Smith J . Linkage disequilibrium and recombination in hominid mitochondrial DNA Science 1999 286: 2524–2525
Hey J . Human mitochondrial DNA recombination: can it be true? Trends Ecol Evol 2000 15: 181–182
Strauss E . mtDNA shows signs of paternal influence Science 1999 286: 2436
Awadalla P, Eyre-Walker A, Maynard Smith J . Questioning evidence for recombination in human mitochondrial DNA Science 2000 288: 1931a
Eyre-Walker A . Do mitochondria recombine in humans? Phil Trans Roy Soc Lond B 2000 355: 1573–1580
Kivisild T, Villems R . Questioning evidence for recombination in human mitochondrial DNA Science 2000 288: 1931a
Jorde LB, Bamshad M . Questioning evidence for recombination in human mitochondrial DNA Science 2000 288: 1931a
Kumar S, Hedrick PW, Dowling T, Stoneking M . Questioning evidence for recombination in human mitochondrial DNA Science 2000 288: 1931a
Parsons TJ, Irwin JA . Questioning evidence for recombination in human mitochondrial DNA Science 2000 288: 1931a
Hedrick PW . Genetics of populations (2nd ed) Jones and Bartlett, Boston 2000
Weinberg W . Uber Vererbungsgesetze beim Menschen Z Abst V Vererb 1909 1: 277–330
Lewontin RC, Kojima K . The evolutionary dynamics of complex polymorphisms Evolution 1960 14: 450–472
Lewontin RC . The interaction of selection and linkage. 1. General considerations; heterotic models Genetics 1964 49: 49–67
Hill WG, Robertson A . Linkage disequilibrium in finite populations Theoret Appl Genet 1968 38: 226–231
Hedrick PW . Inference of recombinational hotspots using gametic disequilibrium values Heredity 1988 60: 435–438
Elson, JL, Andrews, RM, Chinnery PF, Lightowlers, RN, Turnbull DM, Howell N . Analysis of European mtDNAs for recombination Am J Hum Genet 2001 68: 145–153
Ingman M, Kaessmann H, Paabo S, Gyllensted U . Mitochondrial genome variation and the origin of modern humans Nature 2000 408: 708–713
Lewontin RC . The detection of linkage disequilibrium in molecular sequence data Genetics 1995 140: 377–388
Kumar S . LDA: Linkage Disequilibrium Analysis, Version 1.0, Arizona State Univ., Tempe, AZ 2000
Acknowledgements
We would like to thank T Dowling, R Lewontin and M Stoneking for discussions on this topic. P Hedrick has been supported by the Ullman Professorship and S Kumar by NIH, NSF, and Burroughs-Wellcome Fund grants for this research.
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Hedrick, P., Kumar, S. Mutation and linkage disequilibrium in human mtDNA. Eur J Hum Genet 9, 969–972 (2001). https://doi.org/10.1038/sj.ejhg.5200735
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DOI: https://doi.org/10.1038/sj.ejhg.5200735
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