Abstract
There is now a vast amount of empirical research, some of it quite old, to show that non-controlled studies are much more likely to reach a distorted or inflated view of effectiveness.
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Shaw, B. How relevant is the evidence-based process to orthodontics. Evid Based Dent 2, 7–8 (2000). https://doi.org/10.1038/sj.ebd.6400004
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DOI: https://doi.org/10.1038/sj.ebd.6400004
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