Figure 9

Influence of pH on cytotoxicity of CMX. The CMX pH of 8.1 was adjusted with HCl to that of control medium at 7.7. Conditioned media of 96 h were tested for the growth-promoting capacity as described in Figure 1. Ammonia concentrations in CMX (8 Gy 50 000 cells) and in the medium conditioned without cells (closed circles) were 4.6 and 1.5 mM, respectively.