Table 3 Significance levels (Fisher's exact test; P-values) of association between IHC-detected marker expression (sample before FE120C) and response by clinical, pathological and integrated assessment, all dichotomised and thus crosstabulated

From: Breast cancer response to neoadjuvant chemotherapy: predictive markers and relation with outcome

 

Clinical cCR vs non-cCR

Pathological Any vs none

Combination I–III vs IV–VII

ER (n=53)

0.73

0.04 *

0.02 *

 Positive 34

 

Any 18; None 16

I–III 2; IV–VII 32

 Negative 19

 

Any 16; None 3

I–III 6; IV–VII 13

P53 (n=53)

0.07

0.04 *

0.05 *

 Positive 22

 

Any 18; None 4

I–III 6; IV–VII 16

 Negative 31

 

Any 16; None 15

I–III 2; IV–VII 29

Ki-67 (n=53)

0.03 *

0.78

0.02 *

 High 24

CR 8; non-CR 16

 

I–III 7; IV–VII 17

 Low 29

CR 2; non-CR 27

 

I–III 1; IV–VII 28

Bcl-2 (n=49)

0.24

1.0

1.0

HER2 (n=53)

0.25

0.76

1.0

  1. *Association is statistically significant at the 0.05 level.
Back to article page