Figure 1
From: Cell proliferation is related to in vitro drug resistance in childhood acute leukaemia
Comparison of S-phase fractions of peripheral blood (PB) vs bone marrow (BM) samples. Represented are the percentages of cells in S phase for the ALL and AML samples derived from BM or PB. The median value is shown as horizontal bar. Both the initial and relapse ALL samples as well as the initial AML samples derived from BM had a significantly higher S-phase fraction than those derived from PB (*, +, #; P<0.01). The BM-derived ALL samples taken at initial diagnosis differed significantly from those taken at relapsed disease in the S-phase fraction (**; P<0.01). In addition, the BM-derived ALL samples taken at initial diagnosis differed significantly from the initial AML samples (++; P<0.05). iALL and iAML, samples taken at initial diagnosis; rALL and rAML, samples taken at relapsed disease.
