Figure 1
From: L523S, an RNA-binding protein as a potential therapeutic target for lung cancer
(A) Microarray analysis of L523S. Pseudocolour images of hybridisation intensities (white being the strongest and black being the weakest) were shown between 23 pairs of probes in Cy3 and Cy5 channels as indicated. (B) Real-time PCR analysis of L523S in NSCLC using an extended panel of 66 cDNA samples for LSCC. Overexpression is defined as ⩾10-fold expression compared with average expression in all normal tissues, or ⩾three-fold expression compared with highest expression in normal tissues. Overexpression of L523S was detected in 21 of 26 squamous tumours with 24 being LSCC. Expression of L523S was not associated with stages of the disease. (Figure continued on next page.)
