Table 3 Polymorphisms in the ST7 gene locus detected in this study

From: Mutations in the ST7/RAY1/HELG locus rarely occur in primary colorectal, gastric, and hepatocellular carcinomas

  

Allele frequency

Location

Nt

CRC

GC

HCC

Intron 8 (−31 nt from exon 9)

A/T

0.05/0.95

0.02/0.98

0.03/0.97

Intron 10 (+8 nt from exon 9)

T/C

0.20/0.80

0.20/0.80

0.18/0.82

Intron 11 (+17 nt from exon 10)

C/T

0.20/0.80

0.20/0.80

0.16/0.84

Intron 15 (+28 nt from exon 14)

T/G

0.00/1.00

0.01/0.99

0.00/1.00

  1. nt=nucleotide; CRC=colorectal cancer; GC=gastric cancer; HCC=hepatocellular carcinoma. Allele frequency was determined in each of the 48 cancers.
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