Table 1 Verbal, visuomotor and memory performances in patients (n=25) and controls (n=52): comparison at baseline, and testing of patients from baseline through 12 months (means (s.e.'s))

From: Androgen deprivation and cognition in prostate cancer

   

Patients

 

Controls

P -value Controls/patients

Baseline

6 months

12 months

P -value Total period

Pairwise comparisons P <0.05 a

Similarities

19.9(0.39)

0.511

20.2 (0.64)

20.2 (0.65)

21.6 (0.66)

0.037

6<12

Digit span

10.9 (0.30)

0.008

9.5 (0.32)

10.1 (0.33)

10.5 (0.33)

0.062

 

Digit symbol

37.3 (1.25)

0.011

30.9 (2.03)

31.5 (2.07)

34.2 (2.05)

0.166

 

Block design

32.4 (1.12)

0.497

30.0 (1.73)

31.3 (1.74)

31.7 (1.75)

0.260

 

Object naming (s)

33.7 (1.23)

0.656

36.3 (2.23)

37.1 (2.29)

33.5 (2.27)

0.316

 

Object recall (immediate)

12.1 (0.32)

0.412

12.4 (0.45)

13.6 (0.47)

13.8 (0.46)

0.035

B<6

Object recall (delayed)

10.1 (0.31)

0.927

10.4 (0.56)

11.9 (0.57)

12.3 (0.56)

0.001

B<6;B<12

Deterioration score

0.80 (0.28)

0.922

0.84 (0.25)

0.94 (0.26)

0.43 (0.26)

0.245

 

Verbal fluencyb

27.3 (2.36)

0.049

21.3 (1.08)

22.0 (1.10)

21.9 (1.08)

0.791

 

Picture namingb

13.3 (0.58)

0.874

13.4 (0.31)

13.4 (0.32)

13.7 (0.31)

0.281

 

Word list recallb

19.3 (1.26)

0.242

21.0 (0.78)

21.1 (0.80)

20.8 (0.79)

0.875

 

Benton, visual recognition (correct)

  

5.2 (0.25)

5.6 (0.26)

5.4 (0.26)

0.158

 

Visual span (Wechsler memory scale)

  

15.8 (0.61)

16.0 (0.62)

15.4 (0.62)

0.534

 

Mini-mental state

28.0 (0.20)

0.147

27.1 (0.40)

27.5 (0.40)

27.6 (0.40)

0.611

 

Beck depression score

2.7 (0.33)

0.780

2.8 (0.53)

2.5 (0.55)

2.2 (0.54)

0.753

 
  1. B=baseline; 6=6 month-testing; s.e.=standard error; s=second; 12=12 month-testing;
  2. aTukey's multiple comparison corrected.
  3. bNumber of controls=12.
Back to article page