Table 2 Tumour formation incidence of OSE cells and gene-transfected OSE cells injected into nude mice

From: C-erbB-2 or mutant Ha-ras induced malignant transformation of immortalized human ovarian surface epithelial cells in vitro

Groups

BALB/C nude mice

OSE cells

0/10(0%)

OSE cells+LT

0/10(0%)

OSE cells+LT+hTERT

0/10(0%)

OSE cells+LT+hTERT+Ha-ras

4/10(40%)

OSE cells+LT+hTERT+c-erbB-2

5/10(50%)

A2780

10/10(100%)

  1. Cells were subcutaneously injected into nude mice. The results are presented as number of mice with tumour formation/total number of mice injected with OSE cells with or without gene transfection, with this value expressed as a percentage in parentheses. OSE cells+LT=LT-transfected OSE cells; OSE cells+LT+hTERT=OSE cells transfected with a combination of LT and hTERT. OSE cells+LT+hTERT+Ha-ras=OSE cells transfected with a combination of LT, hTERT and mutant Ha-ras; OSE cells+LT+hTERT+c-erbB-2=OSE cells transfected with a combination of LT, hTERT and c-erbB-2; A2780=ovarian cancer cell line.
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