Table 1 Clinical characters of patients treated with CHOP or MACOP-B/VACOP-B

From: Primary mediastinal large B-cell lymphoma (PMLBCL): long-term results from a retrospective multicentre Italian experience in 138 patients treated with CHOP or MACOP-B/VACOP-B

 

CHOP

MACOP-B/VACOP-B

P

Patients

43

95

 

Median age

35 (17–70)

36.5 (14–65)

 

Gender (F/M)

27/16 (1.68)

48/47 (1.02)

 

B symptoms

9/43 (20.9%)

48/95 (50.5%)

0.002

Bulky mediastinum

32/43 (74.4%)

79/95 (83.1%)

n.s.

Pleural effusion

19/43 (44.1%)

43/95 (45.2%)

n.s.

Pericardial effusion

9/43 (20.9%)

28/95(29.4%)

n.s.

SVCS

25/43 (58.1%)

43/95 (45.2%)

n.s.

Stage I–II

29/43 (67.4%)

66/95 (69.4%)

n.s.

Stage III–IV

14/43 (32.5%)

29/95 (30.5%)

n.s.

IPI

 Low/low-intermediate

25/39 (64.1%)

62/92 (67.3%)

n.s.

 High-intermediate/high

14/39 (35.8%)

30/92 (32.6%)

n.s.

Study period

 1982–1990

26 (60.5%)

45 (47.3%)

n.s.

 1991–1999

17 (39.5%)

50 (52.6%)

n.s.

Median follow-up (censored patients)

78 mo (8–199+)

91.5 mo (10–172+)

Â