Table 1 Clinical characters of patients treated with CHOP or MACOP-B/VACOP-B
| Â | CHOP | MACOP-B/VACOP-B | P |
|---|---|---|---|
Patients | 43 | 95 | Â |
Median age | 35 (17–70) | 36.5 (14–65) |  |
Gender (F/M) | 27/16 (1.68) | 48/47 (1.02) | Â |
B symptoms | 9/43 (20.9%) | 48/95 (50.5%) | 0.002 |
Bulky mediastinum | 32/43 (74.4%) | 79/95 (83.1%) | n.s. |
Pleural effusion | 19/43 (44.1%) | 43/95 (45.2%) | n.s. |
Pericardial effusion | 9/43 (20.9%) | 28/95(29.4%) | n.s. |
SVCS | 25/43 (58.1%) | 43/95 (45.2%) | n.s. |
Stage I–II | 29/43 (67.4%) | 66/95 (69.4%) | n.s. |
Stage III–IV | 14/43 (32.5%) | 29/95 (30.5%) | n.s. |
IPI | |||
 Low/low-intermediate | 25/39 (64.1%) | 62/92 (67.3%) | n.s. |
 High-intermediate/high | 14/39 (35.8%) | 30/92 (32.6%) | n.s. |
Study period | |||
 1982–1990 | 26 (60.5%) | 45 (47.3%) | n.s. |
 1991–1999 | 17 (39.5%) | 50 (52.6%) | n.s. |
Median follow-up (censored patients) | 78 mo (8–199+) | 91.5 mo (10–172+) |  |