Figure 2 | British Journal of Cancer

Figure 2

From: 2-Amino metabolites are key mediators of CB 1954 and SN 23862 bystander effects in nitroreductase GDEPT

Figure 2

Extracellular metabolites of CB 1954 in V79-NTRpuro cell suspensions (5 × 106 ml−1, 3 h). (A) Absorbance chromatogram at 330 nm (lower) and biochromatogram (upper) determined using a 1 : 135 dilution of HPLC fractions into UV4 cell cultures. U1, unknown product; *phenol red. (B) Comparison of cytotoxicity of the bioactive extracellular products. The abscissa is the dilution factor in the bioassay.

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