Table 2 Frequencies of loss of heterozygosity according to histological subtype

From: Allelic losses on chromosome 3p are accumulated in relation to morphological changes of lung adenocarcinoma

  

LOH (%)

Marker

Region

PAPa type

BACa type

D3S1597

3p25

8/12(66.7)

4/7(57.1)

D3S2432

3p22–24

6/13(46.2)

7/17(41.2)

D3S1612

3p22–24

2/2(100)

1/1(100)

D3S1478

3p21.3

11/15(73.3)

4/12(33.3)

D3S4597

3p21.3

2/2(100)

4/7(57.1)

D3S4622

3p21.3

7/9(77.8)

2/3(66.7)

D3S1573

3p21.2–21.3

7/11(63.6)

6/11(54.5)

D3S1234

3p14.2

9/14(64.3)

1/8(12.5)

D3S1274

3p12

8/14(57.1)

2/8(25.0)

 

Any region

18/19(94.7)

12/17(70.6)

  1. Poorly differentiated tumours were excluded from this analysis.
  2. aPAP=papillary; BAC=bronchioloalveolar carcinoma.
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