Figure 4 | British Journal of Cancer

Figure 4

From: Cooperative stimulation of vascular endothelial growth factor expression by hypoxia and reactive oxygen species: the effect of targeting vascular endothelial growth factor and oxidative stress in an orthotopic xenograft model of bladder carcinoma

Figure 4

Immunohistochemical staining of the oxidative stress markers haem oxygenase-1 (HO-1) and 4-hydroxy-2-nonenal in RT112-TP tumours. The top panel is a low-power view with haematoxylin stain. The arrows indicate the sections stained for HO-1 (middle panel) and 4-hydroxy-2-nonenal (lower panel). The ex vivo RT112-TP tumour stained positive for both HO-1 and 4-hydroxy-2-nonenal. All normal tissues examined, including bladder, were negative for these markers (see Results).

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