Figure 1
From: Atiprimod blocks STAT3 phosphorylation and induces apoptosis in multiple myeloma cells

Effect of Atiprimod on activation of NF-κB. U266-B1 cells were incubated for 4 h with increasing concentrations of Atiprimod (A) and with 8 μ M of Atiprimod for 1, 4, 8, 16, and 24 h (B). Nuclear extracts were prepared, and NF-κB activity was analysed by EMSA, as described in Materials and Methods.