Table 1 BMP methylation and k-ras mutation in NSCLC
BMP3B methylation | BMP6 methylation | Concurrent BMP3b and BMP6 methylation | |||||||
|---|---|---|---|---|---|---|---|---|---|
NM a | M a | P -value | NM a | M a | P -value | NM a | M a | P -value | |
Overall prevalence in NSCLC (n (%)) | 68 (44%) | 88 (56%) | 96 (60%) | 63 (40%) | |||||
k-ras mutation (codon 12) | |||||||||
Not mutated (%) | 62 (91) | 69 (78) | 82 (87) | 49 (78) | 93 (89) | 30 (70) | |||
Mutated (%) | 6 (9) | 19 (22) | 0.03b | 12 (13) | 14 (22) | 0.12b | 11 (11) | 13 (30) | 0.003b |
