Table 1 Differentially expressed genes in Ta tumours compared to normal bladder
From: Gene expression profiling of noninvasive primary urothelial tumours using microarrays
Gene transcript | Gene symbol a | Tentative gene function | Probeset ID | P -value | FC b |
|---|---|---|---|---|---|
Keratin 7 | KRT7 | Cytoskeleton organisation | 209016_s_at | 7.51E-11c | 19.8 |
IMP (inosine monophosphate) dehydrogenase 2 | IMPDH2 | RNA binding, spliceosome complex | 201892_s_at | 4.71E-09c | 2.8 |
OGT(O-Glc-NAc transferase)-interacting protein 106 kDa | OIP106 | DNA binding, G -protein coupled receptor protein signalling pathway | 214924_s_at | 7.45E-09c | 3.9 |
Junction plakoglobin | JUP | Cytoskeleton, cell adhesion | 201015_s_at | 8.31E-09c | 2.8 |
Keratin 8 | KRT8 | Cytoskeleton, protein-nucleus import | 209008_x_at | 9.21E-09c | 5.4 |
Protein tyrosine phosphatase, receptor type, F | PTPRF | Transmembrane receptor protein tyrosine phosphatase signalling pathway | 200635_s_at | 1.07E-08c | 2.9 |
Syndecan 1 | SDC1 | Cytoskeletal protein binding, integral to plasma membrane | 201286_at | 1.51E-08c | 3.8 |
High mobility group AT-hook 1 | HMGA1 | Transcription factor | 206074_s_at | 3.48E-08c | 2.2 |
Protein phosphatase1, regulatory (inhibitor) subunit 14B | PPP1R14B | Phosphoprotein inhibitor | 212680_x_at | 4.98E-08c | 2.5 |
Agrin | AGRN | Function unknown | 212285_s_at | 5.18E-08c | 2.1 |
Fatty acid binding protein 6, ileal (gastrotropin) | FABP6 | Heat shock protein activity, protein folding | 210445_at | 6.90E-08c | 3.5 |
Slingshot 3 | SSH-3 | Acid phosphatase activity | 219241_x_at | 7.99E-08c | 2.0 |
EST | Function unknown | 216379_x_at | 9.99E-08c | 3.1 | |
Syndecan 1 | SDC1 | Cytoskeletal protein binding, integral to plasma membrane | 201287_s_at | 1.16E-07c | 4.3 |
Hypoxia-inducible factor prolyl 4-hydroxylase | PH-4 | Oxidoreductase activity | 222125_s_at | 1.33E-07c | 2.0 |
G-rich RNA sequence binding factor 1 | GRSF1 | Isomerase activity, protein folding | 201520_s_at | 1.51E-07c | 3.6 |
CD24 antigen (small-cell lung carcinoma cluster 4 antigen) | CD24 | Cytoplasm, transferase activity | 209771_x_at | 1.67E-07c | 3.1 |
Lamin A/C | LMNA | Protein kinase C activation, transferase activity | 203411_s_at | 1.82E-07c | 2.2 |
FAT tumour suppressor homolog 1 (Drosophila) | FAT | Negative regulation of cell cycle | 201579_at | 1.94E-07c | 3.2 |
Aminoacylase 1 | ACY1 | Metallopeptidase activity | 202740_at | 2.11E-07c | 2.4 |
