Table 2 Informative genes that distinguish high grade Ta tumours from PUNLMP/low grade Ta tumours
From: Gene expression profiling of noninvasive primary urothelial tumours using microarrays
Gene transcript | Gene symbol a | Tentative gene function | Probeset ID | P -value | FC b |
|---|---|---|---|---|---|
Hypothetical protein FLJ13725 | FLJ13725 | Function unknown | 45749_at | 3.87E-05c | 0.7 |
Cyclin-dependent kinase 4 | CDK4 | Regulation of cell cycle | 202246_s_at | 4.56E-05c | 1.4 |
Ras homologue gene family, member Q | ARHQ | GTP binding, Rho small monomeric GTPase activity | 212119_at | 9.17E-05c | 1.7 |
Diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) | DBI | Benzodiazepine receptor binding | 202428_x_at | 1.20E-04c | 1.9 |
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | YWHAZ | Protein domain specific binding | 200640_at | 1.39E-04c | 1.6 |
H2A histone family, member Z | H2AFZ | DNA binding, nucleosome assembly, nucleus | 213911_s_at | 2.02E-04c | 2.4 |
Diazepam binding inhibitor (GABA receptor modulator, acyl-coenzyme A binding protein) | DBI | Benzodiazepine receptor binding | 211070_x_at | 2.42E-04c | 2.0 |
Voltage-dependent anion channel 3 | VDAC3 | Voltage-dependent anion channel porin activity | 208845_at | 2.46E-04c | 1.4 |
Hypothetical protein MAC30 | MAC30 | Regulation of cell growth | 212282_at | 4.50E-04c | 3.1 |
Interleukin enhancer binding factor 2, 45 kDa | ILF2 | RNA polymerase II transcription factor activity, nucleus | 200052_s_at | 4.51E-04c | 1.8 |
Likely ortholog of mouse immediate early response, erythropoietin 4 | LEREPO4 | Nucleic acid binding | 201593_s_at | 5.11E-04c | 1.7 |
Hypothetical protein MAC30 | MAC30 | Regulation of cell growth | 212281_s_at | 5.92E-04c | 3.6 |
Proteasome (prosome, macropain) subunit, beta type, 7 | PSMB7 | Endopeptidase activity, ubiquitin-dependent protein catabolism | 200786_at | 6.85E-04c | 1.7 |
Transgelin 2 | TAGLN2 | Muscle development | 200916_at | 7.64E-04c | 1.6 |
Proteasome (prosome, macropain) subunit, alpha type, 6 | PSMA6 | RNA binding, endopeptidase activity, ubiquitin-dependent protein catabolism | 208805_at | 8.10E-04c | 1.4 |
Aldo-keto reductase family 1, member A1 (aldehyde reductase) | AKR1A1 | Oxidoreductase activity | 201900_s_at | 8.22E-04c | 1.3 |
Peroxiredoxin 1 | PRDX1 | Cell proliferation, peroxidase activity | 208680_at | 8.23E-04c | 1.5 |
Chromosome 13 open reading frame 12 | C13orf12 | Function unknown | 217769_s_at | 8.42E-04c | 1.4 |
Jun D proto-oncogene | JUND | Regulation of transcription from Pol II promoter, transcription factor activity | 203752_s_at | 8.57E-04c | 1.8 |
Formin binding protein 3 | FNBP3 | mRNA splicing, signal transduction | 213729_at | 8.78E-04c | 1.9 |
