Table 4 Comparison of the most associated SNP (number 2, rs228589) between the study's subgroups: case vs control, and asymptomatic high-risk vs control
From: ATM haplotypes and breast cancer risk in Jewish high-risk women
Alleles (%) | RR (95% CI) | OR (95% CI) | ||||
|---|---|---|---|---|---|---|
Study subset | A | T | A | T | A | T |
Breast cancer case vs control | 88 (67) | 44 (33) | 0.34 (0.27–0.42) | 2.97 (2.4–3.69) | 0.08 (0.04–0.17) | 12.61 (5.91–26.92) |
227 (96) | 9 (4) | |||||
Asymptomatic high risk vs control | 76 (51) | 72 (49) | 0.28 (0.23–0.35) | 3.45 (2.87–4.37) | 0.04 (0.02–0.09) | 23.89 (11.4–50.08) |
227 (96) | 9 (4) | |||||
All high-risk women vs control | 303 (79) | 81 (21) | 0.45 (0.4–0.51) | 2.21 (1.95–2.51) | 0.06 (0.03–0.11) | 17.84 (8.79–36.19) |
227 (96) | 9 (4) | |||||
