Table 10 Comparison of the short haplotypes between the study's subgroups: (A) case vs control, and asymptomatic high-risk vs control (Table 5B) and (B) all high-risk vs control (Table 5C)
From: ATM haplotypes and breast cancer risk in Jewish high-risk women
Haplotypes (%) | RR (95% CI) | OR (95% CI) | |||||||
|---|---|---|---|---|---|---|---|---|---|
Study subset | A | B | C | A | B | C | A | B | C |
(A) | |||||||||
Breast cancer case | 74 (56) | 44 (33) | 14 (0.6) | 0.61 (0.49–0.76) | 8.74(3.32–23.02) | 2.28 (0.78–6.67) | 0.12(0.05–0.27) | 12.61(4.32–36.84) | 2.43(0.76–7.74) |
Vs control | 216 (91) | 9 (4) | 11 (4.6) | ||||||
Asymptomatic high risk | 93 (61) | 37 (24) | 22 (14.5) | 0.66 (0.55–0.81) | 6.38 (2.37–17.16) | 3.11(1.16–8.29) | 0.146 (0.07–0.32) | 8.115 (2.76–23.85) | 3.461 (1.19–10.07) |
Vs control | 216 (91) | 9 (4) | 11 (4.6) | ||||||
(B) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Haplotypes (%) | RR (95% CI) | OR (95% CI) | |||||||
Study subset | D | E | F | D | E | F | D | E | F |
All high-risk women | 206 (73) | 78 (27) | 0 (0) | 0.9 (0.82–0.99) | 7.2 (3.69–14.05) | — | 0.62 (0.41–0.94) | 9.55 (4.67–19.5) | — |
Vs control | 191 (81) | 9 (4) | 36 (15) | ||||||
