Table 2 Results from interphase FISH analysis of the 12 cervical adenocarcinomas
From: Frequent gain of the human telomerase gene TERC at 3q26 in cervical adenocarcinomas
Signals per cell: mean (range) | Relative TERC vs | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Case no | Nuclei counted | ‘Diploid’ (2-2-2) (%) | ‘Nondiploid’a (%) | ‘Tetraploid’ (4-4-4) (%) | Nuclei with >2 TERC (%) | ‘Nondiploid’ with >2 TERC (%) | CEP7 | CEP3 | TERC | CEP7 | CEP3 | Most common ‘nondiploid’ patterns |
1 | 376 | 33 | 67 | 1 | 66 | 99 | 2.2 (2–5) | 2.2 (2–5) | 3.0 (2–8) | 1.4 | 1.4 | (2-2-3) (2-2-4) |
2 | 391 | 31 | 69 | 0 | 64 | 92 | 2.1 (2–4) | 2.1 (2–4) | 3.2 (2–7) | 1.5 | 1.6 | (2-2-4) (2-2-3) (2-2-5) |
3 | 215 | 27 | 73 | 12 | 68 | 94 | 3.0 (2–6) | 3.1 (2–8) | 3.3 (2–9) | 1.1 | 1.1 | (4-4-4) (4-3-4) (4-3-3) (3-3-3) (3-4-4) |
4 | 466 | 40 | 60 | 0 | 59 | 99 | 2.0 (1–4) | 3.2 (2–5) | 4.4 (2–12) | 2.1 | 1.4 | (2-4-6) (2-3-5) (2-4-5) (2-4-7) |
5 | 336 | 68 | 32 | 1 | 27 | 86 | 2.1 (2–4) | 2.1 (2–4) | 2.4 (2–6) | 1.1 | 1.1 | (2-2-3) (2-2-4) (2-3-2) |
6 | 641 | 69 | 31 | 1 | 28 | 92 | 2.0 (0–4) | 2.3 (2–8) | 2.6 (2–8) | 1.3 | 1.1 | (2-3-4) (2-3-5) (2-2-3) (2-3-3) |
7 | 412 | 28 | 72 | 0 | 71 | 99 | 2.1 (2–4) | 2.1 (2–8) | 4.2 (2–15) | 2.0 | 2.0 | (2-2-5) (2-2-4) (2-2-6) (2-2-3) |
8 | 626 | 46 | 54 | 1 | 54 | 98 | 2.0 (2–4) | 2.2 (2–5) | 2.9 (2–12) | 1.4 | 1.3 | (2-2-4) (2-2-3) (2-3-3) (2-2-5) |
9 | 253 | 29 | 71 | 0 | 64 | 91 | 2.6 (2–5) | 3.0 (2–7) | 3.4 (2–11) | 1.3 | 1.1 | (2-2-3) (2-3-3) (2-2-4) (3-2-2) (3-4-4) |
10 | 286 | 30 | 70 | 0 | 66 | 95 | 2.7 (2–7) | 2.9 (2–7) | 5.2 (2–22) | 2.0 | 1.8 | (2-2-4) (2-2-3) (2-2-5) (2-2-6) |
11 | 393 | 79 | 21 | 4 | 18 | 83 | 2.2 (2–6) | 2.2 (2–6) | 2.3 (2–6) | 1.04 | 1.04 | (2-2-3) (4-4-4) (2-3-2) |
12 | 208 | 20 | 80 | 0 | 79 | 99 | 1.9 (0–4) | 2.0 (0–5) | 3.0 (2–7) | 1.6 | 1.5 | (2-2-3) (2-2-4) |
