Table 1 Telomerase activity in relation to HPV status in invasive, dysplastic and normal cervical lesions
Type of cervical lesion | HR-HPV 16/18 | Telomerase activity | ||||
|---|---|---|---|---|---|---|
| Â | Positve | Negative | OR ( P -value) | Positive | Negative | OR ( P -value) |
(a) | (b) | (c) | (d) | (e) | (f) | (g) |
Invasive cervical carcinomas (n=59) | 52 (88.1%) | 7 (11.9%) | 141.1 (<0.001) | 59 (100.0%) | 0 | —a (<0.001) |
Severe (Severe dysplasia and CIS) (n=26) | 20 (76.9)% | 6 (23.1%) | 63.3 (<0.001) | 26 (100%) | 0 | —a (<0.001) |
Moderate (n=18) | 10 (55.5%) | 8 (44.5%) | 23.8 (<0.001) | 18 (100%) | 0 | —a (<0.001) |
Mild dysplasia (n=11) | 6 (54.5%) | 5 (45.5%) | 22.8 (<0.001) | 7 (63.6%) | 4 (36.4%) | 32.3 (<0.001) |
Normal cervical tissues (n=40) | 2 (5.0%) | 38 (95.0%) | — | 2 (5%) | 38 (95.0%) | — (<0.001) |
