Table 2 Univariate analysis of pre- and postoperative parameters as well as Tiam1 overexpression

From: Prognostic relevance of Tiam1 protein expression in prostate carcinomas

Parameter

χ 2

P -value

Hazard ratio

95% CI

Age

1.658

0.202

1.058

0.970–1.155

Preoperative PSA

4.174

0.044*

1.035

1.001–1.070

pT

9.451

0.006*

5.805

1.657–20.339

pN

3.726

0.091

6.098

0.750–50

GS

12.685

0.001*

2.121

1.369–3.286

PNI

2.105

0.164

2.907

0.646–13.158

BVI

0.592

0.612

21.639

0.000–3126101

LVI

2.323

0.142

2.604

0.725–9.346

Tiam1 overexpression

5.531

0.030*

4

1.15–13.89

  1. CI, confidence interval.
  2. *Statistically significant. Cox proportional hazard model and single parameter analysis was used to determine the prognostic significance of age, preoperative PSA, LVI (+/−), BVI (+/−), PNI (+/−), pT stage (pT3/pT2), pN stage (pN1/pN0), GS, and Tiam1 overexpression (3.5-fold/<3.5-fold). Age, preoperative PSA and GS were used as continuous variables.