Figure 1 | British Journal of Cancer

Figure 1

From: Estimating the long-term impact of a prophylactic human papillomavirus 16/18 vaccine on the burden of cervical cancer in the UK

Figure 1

Simplified structure of the human papillomavirus (HPV) and cervical cancer natural history model. Model simulates the natural history of HPV infection and cervical carcinogenesis while incorporating the underlying type-specific HPV distribution within each stage of cervical disease, by use of a sequence of 6-month transitions among mutually exclusive health states. The probabilities governing each of these transitions are conditional on the type of HPV infection and age. Transitions to death owing to natural causes can occur from any health state in the model.

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