Table 1 AIP changes identified in colorectal, breast, and prostate tumour samples
Cancer type | Number of patients with a variant | Location | Nucleotide change | Amino-acid change | Individuals (allele frequencies) | Controls (allele frequencies) |
|---|---|---|---|---|---|---|
Colorectal | 2 | Exon 1 | 47G>A | R16H | 2/373 (0.27%) | 0/209 |
| Â | 6 | Exon 1 | 68G>A | G23E | 6/373 (0.8%) | 5/209 (1.2%) |
|  | 1 | 5′ UTR | −5G>C | — | 1/373 (0.13%) | 0/209 |
|  | 2 | 3′ UTR | +60G>C (heterozygous) | — | 2/373 (0.27%) | 3/182 (0.8%) |
Breast | 1 | Intron 3 | IVS3+15C>T | — | 1/43 (1.16%) | NA |
|  | 5 | 3′ UTR | +60G>C (heterozygous) | — |  |  |
|  | 1 |  | +60G>C (homozygous) | — | 6/81 (4.3%) | 3/182 (0.8%) |
Prostate | 1 | Exon 1 | 36G>A | G12G | 1/44 (1.14%) | 0/209 |
| Â | 1 | Exon 5 | 714C>T | C238C | 1/44 (1.14%) | NA |
