Table 2 Germline CEB1 mutation rate in parents of childhood leukaemia cases and controls

From: New germline mutations in the hypervariable minisatellite CEB1 in the parents of children with leukaemia

Comparison

Cases

Controls

OR

95% CI

Two-sided P *

Informative family trios (n)

135

124

   

Informative offspring (n)

136

124

   

Paternal alleles (n)

132

122

   

Maternal alleles (n)

131

122

   

Paternal germline mutations

11

19

   

Maternal germline mutations

0

2

   

Paternal mutation rate

0.083 (8.3%)

0.156 (15.6%)

0.50

0.23–1.08

0.11

Maternal mutation rate

0

0.016 (1.6%)

0.18

0.02–1.79

0.463

Parental mutation rate

0.041 (4.1%)

0.086 (8.6%)

0.47

0.23–0.98

0.061

  1. CI, confidence interval; n, number; OR, odds ratio.
  2. *Two-sided P value in Fisher's exact test.
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