Table 3 Paternal CEB1 germline mutation rate in relation to childhood leukaemia subtype

From: New germline mutations in the hypervariable minisatellite CEB1 in the parents of children with leukaemia

Leukaemia subtype

Paternal alleles

Paternal mutations

Paternal mutation rate

OR

95% CI

Two-sided P

BCP ALL

93

9

0.097 (9.7%)

0.60

0.27–1.34

0.28

Pro-B ALL

8

0

0

0.31

0.04–2.60

0.54

T ALL

18

2

0.111 (11.1%)

0.80

0.22–0.46

0.93

AML

13

0

0

—

—

—

Total cases

132

11

0.083 (8.3%)

0.50

0.23–1.08

0.11

Controls

122

19

0.156 (15.6%)

   
  1. AML, acute myeloid leukaemia; BCP ALL; B-cell precursor ALL; Pro-B ALL, progenitor B-cell ALL; T ALL, T-cell ALL.
  2. aLeukaemia subtype in relation to paternal allele mutation rate.
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