Table 3 Immunohistochemical analysis for p-S6K, p-S6, S6K and p-AKT in ESCC tissues

From: Increased phosphorylation of p70 S6 kinase is associated with HPV16 infection in cervical cancer and esophageal cancer

   

IHC score

 

Group

Total number

IV

III

II

I

0

⩾1 (%)

P

⩾2 (%)

P

p-S6K

HPV16+

97

6

5

4

11

71

26 (26.8)

 

15 (15.5)

 
 

HPV16−

64

1

1

2

1

59

5 (7.8)

0.005

4 (16.3)

0.128

p-S6

HPV16+

97

2

1

5

15

74

23 (23.7)

 

8 (8.2)

 
 

HPV16−

64

0

0

2

7

55

9 (14.1)

0.194

2 (3.1)

0.325

S6K

HPV16+

97

9

12

15

24

37

60 (61.9)

 

36 (37.1)

 
 

HPV16−

64

6

10

7

13

28

36 (56.3)

0.586

23 (35.9)

1.000

p-Akt

HPV16+

97

0

0

0

6

91

6 (6.2)

 

0

 
 

HPV16−

64

0

0

0

3

61

3 (4.7)

0.957

0

1.000