Table 3 Immunohistochemical analysis for p-S6K, p-S6, S6K and p-AKT in ESCC tissues
IHC score | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Group | Total number | IV | III | II | I | 0 | ⩾1 (%) | P | ⩾2 (%) | P | |
p-S6K | HPV16+ | 97 | 6 | 5 | 4 | 11 | 71 | 26 (26.8) | 15 (15.5) | ||
HPV16− | 64 | 1 | 1 | 2 | 1 | 59 | 5 (7.8) | 0.005 | 4 (16.3) | 0.128 | |
p-S6 | HPV16+ | 97 | 2 | 1 | 5 | 15 | 74 | 23 (23.7) | 8 (8.2) | ||
HPV16− | 64 | 0 | 0 | 2 | 7 | 55 | 9 (14.1) | 0.194 | 2 (3.1) | 0.325 | |
S6K | HPV16+ | 97 | 9 | 12 | 15 | 24 | 37 | 60 (61.9) | 36 (37.1) | ||
HPV16− | 64 | 6 | 10 | 7 | 13 | 28 | 36 (56.3) | 0.586 | 23 (35.9) | 1.000 | |
p-Akt | HPV16+ | 97 | 0 | 0 | 0 | 6 | 91 | 6 (6.2) | 0 | ||
HPV16− | 64 | 0 | 0 | 0 | 3 | 61 | 3 (4.7) | 0.957 | 0 | 1.000 | |