Table 1 Transcriptional activities of κB4, CEA205 and κB4-CEA205 in CRC and normal cells

From: In vitro evaluation of cancer-specific NF-κB-CEA enhancer–promoter system for 5-fluorouracil prodrug gene therapy in colon cancer cell lines

 

LoVo

Caco2

H630

HCT116

HCT15

HT29

DLD-1

RKO

EAhy926

HUVEC

HMEC

HNEpC

pκB4-Luc

5.6±0.7

13.0±4.5

13.0±2.7

14.0±2.1

13.8±4.0

2.3±0.7

34.4±3.4

12.2±0.3

1.0±0.5

1.0±0.08

1.0±0.08

0.7±0.003

pCEA205-Luc

20.4±8.3

31.3±5.1

31.3±4.7

101.1±5.2

72.8±5.3

11.3±2.0

191.3±18.9

42.0±2.3

1.1±0.6

1.1±0.02

1.1±0.02

2.3±0.01

pκB4-CEA205-Luc

180.6±23.9

183.9±16.9

183.9±2.6

379.3±21.4

558.3±83.8

19.6±6.4

993.6±68.1

207.4±3.8

1.0±0.003

0.95±0.003

0.95±0.003

1.8±0.02

  1. The data represent mean relative luciferase units from three replicates±s.d.