Table 3 The cytotoxicity of 5′-DFUR on the stably transfected CRC cell lines

From: In vitro evaluation of cancer-specific NF-κB-CEA enhancer–promoter system for 5-fluorouracil prodrug gene therapy in colon cancer cell lines

   

pFastBacDualΔpromoter/ κ B4-CEA205-TP

 

pcDNA3

pcDNA3/TP

C1

C2

H630

27.7±12.9

0.94±0.54

0.96±0.02

0.94±0.03

RKO

28.3±13.2

1.16±0.71

0.90±0.07

1.00±0.06

  1. The data represent the mean IC50 (μm) of 5′-DFUR from three replicates±s.d. C1 and C2: clones 1 and 2.