Figure 1
Comparison of the intensity of peptide signals originating from the same protein molecule in each group detected by LC-MS. The vertical axis indicates normalised signal intensity measured by LC-MS. In each box plot, the upper and lower sides of the box represent the upper and the lower quartile values (Q3/Q1), and the upper and lower horizontal bars outside the box indicate the upper and the lower adjacent values (UAV/LAV). Note that UAV is the largest observation value that is less than or equal to Q3+1.5 × (Q3–Q1), and LAV is the smallest observation greater than or equal to Q1–1.5 × (Q3–Q1). Black triangle marks represent the median values, and black square marks represent outliers. U0R0: patients without PAC showing no recurrence within 5 years after surgery. U0R1: patients without PAC in showing recurrence within 5 years after surgery. U1R0: patients who received PAC with uracil–tegafur and showed no recurrence within 5 years after surgery. U1R1: patients who received PAC with uracil–tegafur and showed recurrence within 5 years after surgery. (A) These three peptide signals were shown by MS/MS to have originated from myosin IIA. There was a significant difference between the U1R1 and the other groups (P<9.7 × 10−7). (B) These six peptide signals were shown by MS/MS to have originated from vimentin. There was also a significant difference between the U1R1 and the other groups (P<8.3 × 10−6).
