Table 1 Combination index values for the three drug combinations at 50, 75 and 90% inhibition levels on PC-3 cell viability

From: MS-275 synergistically enhances the growth inhibitory effects of RAMBA VN/66-1 in hormone-insensitive PC-3 prostate cancer cells and tumours

 

CI values

Drug combination

50%

75%

90%

VN/66-1+MS-275

0.56

0.18

0.24

VN/66-1 → MS-275

1.85

1.10

0.69

MS-275 → VN/66-1

0.56

1.72

4.74

  1. Arrows indicate the sequence of treatment.
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