Figure 1
From: Expression of SDF-1α and nuclear CXCR4 predicts lymph node metastasis in colorectal cancer
Immunohistochemistry for SDF-1α in the normal colon and in CRC tissues. (A) Weak to negative immunoreactivity is observed in the cytoplasm of non-neoplastic epithelial cells. (B) Immunoreactivity for SDF-1α is also observed in the lymphoid follicle in the colonic mucosa. (C) Strong type: immunoreactivity is strongly detected in the cytoplasm of cancer cells. (D) Weak type: immunoreactivity is weakly detected in the cytoplasm of cancer cells. Immunoreactivity is also observed in the endothelial cells of the tumour stroma. Scale bars=100 μm.
