Figure 3
From: Expression of SDF-1α and nuclear CXCR4 predicts lymph node metastasis in colorectal cancer

Subcellular localisation of CXCR4 in the CRC cell line HT29. (A) Immunohistochemistry. CXCR4 immunoreactivity is detected not only weakly at the plasma membrane but also strongly in the nuclei. (B) Western blot analysis. CXCR4 immunoreactivity is detected not only in the cytoplasmic and membranous (‘cytomembrane’) fraction but also in the nuclear (‘nuclear’) protein fraction from HT29 cells.