Table 3 Comparison of the clinicopathologial features between the CXCR4-positive and CXCR4-negative CRC patients
From: Expression of SDF-1α and nuclear CXCR4 predicts lymph node metastasis in colorectal cancer
Positive ( n =47) | Negative ( n =13) | P -value | |
|---|---|---|---|
Gender | |||
Man | 31 | 10 | 0.522 |
Woman | 16 | 3 | |
Age (years, mean±s.d.) | 64.0±10.8 | 63.2±11.9 | 0.829 |
Tumour location | |||
Colon | 38 | 11 | 0.999 |
Rectum | 9 | 2 | |
Tumour size (cm, mean±s.d.) | 4.3±1.8 | 3.4±2.8 | 0.158 |
Differentiation | |||
Well | 20 | 6 | |
Mod | 24 | 6 | 0.872 |
Por | 3 | 1 | |
UICC stage | |||
I | 3 | 7 | |
II | 18 | 4 | <0.0001 |
III | 11 | 2 | |
IV | 15 | 0 | |
Lymphatic invasion | |||
None | 9 | 6 | 0.070 |
Present | 38 | 7 | |
Venous invasion | |||
None | 19 | 9 | 0.115 |
Present | 28 | 4 | |
Lymph node metastasis | |||
None | 21 | 12 | 0.004 |
Present | 26 | 1 | |