Table 4 Relationship between CXCR4 immunostaining pattern and clinicopathological features in patients with CXCR4-positive CRC
From: Expression of SDF-1α and nuclear CXCR4 predicts lymph node metastasis in colorectal cancer
Nuclear ( n =29) | Cytomembrane ( n =18) | P -value | |
|---|---|---|---|
Gender | |||
Man | 19 | 12 | 0.999 |
Woman | 10 | 6 | |
Age (years, mean±s.d.) | 63.0±11.4 | 65.6±9.9 | 0.419 |
Tumour location | |||
Colon | 21 | 17 | 0.999 |
Rectum | 8 | 1 | |
Tumour size (cm, mean±s.d.) | 4.3±1.7 | 4.2±2.0 | 0.882 |
Differentiation | |||
Well | 9 | 11 | |
Mod | 17 | 7 | 0.028 |
Por | 3 | 0 | |
UICC stage | |||
I | 0 | 3 | |
II | 9 | 9 | 0.022 |
III | 9 | 2 | |
IV | 11 | 4 | |
Lymphatic invasion | |||
None | 3 | 6 | 0.068 |
Present | 26 | 12 | |
Venous invasion | |||
None | 9 | 10 | 0.172 |
Present | 20 | 8 | |
Lymph node metastasis | |||
None | 9 | 12 | 0.036 |
Present | 20 | 6 | |
