Table 2 Most highly expressed genes in relapse pair with de novo 1q gain

From: Investigation of chromosome 1q reveals differential expression of members of the S100 family in clinical subgroups of intracranial paediatric ependymoma

SAGE TAG

Gene ID

Locus

Gene title

R1p

R1r

R2p

R2r

Difference a

GTATGGGCCC

CHI3L1

1q32.1

Chitinase 3-like 1 (cartilage glycoprotein-39)

38

326

30

0

288

AGCAGATCAG

S100A10

1q21.3

S100 calcium-binding protein A10

122

322

76

11

200

ATCAGTGGCT

PSMB4

1q21.3

Proteasome (prosome, macropain) subunit, β type, 4

41

84

41

18

43

TACTTTTGGC

SLC41A1

1q32.1

Solute carrier family 41, member 1

11

34

15

7

23

TCAGTTTGTC

HAX1

1q22

HS1-binding protein

11

34

26

18

23

GAGTGCAGGT

TROVE2

1q31.2

TROVE domain family member 2

31

53

19

18

22

TACAGCACGG

MGST3

1q24.1

Microsomal glutathione S-transferase 3

36

57

7

7

21

GTGTTTACGT

RAB4A

1q42.13

RAB4A, member RAS oncogene family

8

26

15

0

18

TGCAATAAGC

FAM36A

1q44

Protein FAM36A

6

24

22

15

18

TCTTTCCCCA

PHLDA3

1q32.1

Pleckstrin homology -like domain, family A, member 3

0

16

7

3

16

  1. Columns R1p, R1r, R2p and R2r show the tags per 200 000 for the primary sample of relapse pair R1, relapse samples of relapse pair R1, primary sample of relapse pair R2 and the relapse samples of relapse pair R2, respectively.
  2. aThe difference was calculated using the formula (R1r-R1p).