Table 2 Characteristics of lesions found at colonoscopy and iFOBT result (ng ml−1)

From: Cutoff value determines the performance of a semi-quantitative immunochemical faecal occult blood test in a colorectal cancer screening programme

    

Range

Percentile

iFOBT positives (⩾50 ng ml−1)

N

(%)

Mean (95% CI)

Min

Max

25th

Median

75th

Without colonoscopy

98

(19)

455 (326–583)

52

2916

76

144

497

With colonoscopy

428

(81)

434 (377–492)

50

4168

80

175

482

Neither cancer nor adenomasa

134

(31)

314 (239–388)

50

2818

76

125

347

Non-advanced Adenomasb

105

(25)

356 (232–481)

50

4168

69

109

326

Advanced Adenomasc

161

(38)

523 (420–627)

52

3322

100

251

582

Cancerd

28

(7)

785 (563–1008)

59

1871

283

662

1226

 Stage I or II cancer

19

(68)

652 (400–904)

59

1871

280

384

1099

 Stage III or IV cancer

9

(32)

1066 (662–1470)

202

1845

622

1182

1635

  1. Abbreviation: iFOBT, immunochemical faecal occult blood test.
  2. aNeither cancer nor adenomas: colonoscopies without any lesions or only hyperplastic polyps, serrated adenomas or unclassified polyps.
  3. bNon advanced adenomas: colonoscopy with adenomas but without advanced adenomas and cancer.
  4. cAdvanced adenomas: colonoscopies without cancer but with adenomas ⩾10 mm in size, high grade dysplasia or a villous component ⩾20%.
  5. dStaging according to TNM classification: there were only 4 stage II (all stage IIa, none stage IIb) and no stage IV patients. Therefore, stages I and II, and III and IV were combined.
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