Table 2 TS, TP, and ERCC1 by IHC staining

From: Thymidine synthase, thymidine phosphorylase, and excision repair cross-complementation group 1 expression as predictive markers of capecitabine plus cisplatin chemotherapy as first-line treatment for patients with advanced oesophageal squamous cell carcinoma

 

Number of patients with low scores

%

TS

 Area (0–2 vs 3–4)

38/69

55.1

 Intensity (0–1 vs 2–3)

40/69

58.0

TP

 Area (0–2 vs 3)

23/72

31.9

 Intensity (0–2 vs 3)

3/72

4.2

ERCC1

 Area (0–2 vs 3)

22/41

53.7

 Intensity (0–2 vs 3)

14/41

34.1

  1. Abbreviations: ERCC1=excision repair cross-complementation group 1; IHC=immunohistochemical; TP=thymidine phosphorylase; TS=thymidine synthase. Score means multiplying the intensity and extent grades of the IHC.