Table 4 Multivariate Cox-regression hazard model for PFS and OS

From: Thymidine synthase, thymidine phosphorylase, and excision repair cross-complementation group 1 expression as predictive markers of capecitabine plus cisplatin chemotherapy as first-line treatment for patients with advanced oesophageal squamous cell carcinoma

 

PFS

OS

 

P- value

HR

95% CI

P- value

HR

95% CI

 

Low TS score

0.044

2.87

1.03

7.99

0.356

1.22

0.38

3.46

Strong ERCC1

0.004

10.71

2.10

54.71

0.009

3.73

1.39

10.04

Hepatic metastasis

0.118

2.57

0.79

8.41

0.235

1.11

0.03

2.13

  1. Abbreviations: CI=confidence interval; ERCC1=excision repair cross-complementation group 1; HR=hazard ratio; OS=overall survival; PFS=progression-free survival; TS=thymidine synthase.