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The prevalence of avascular necrosis in patients treated with chemotherapy for testicular tumours
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  • Published: 27 November 2001

The prevalence of avascular necrosis in patients treated with chemotherapy for testicular tumours

  • A M Cook1 nAff4,
  • A S K Dzik-Jurasz2,
  • A R Padhani2 nAff5,
  • A Norman3 &
  • …
  • R A Huddart1 

British Journal of Cancer volume 85, pages 1624–1626 (2001)Cite this article

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Abstract

To study the prevalence of avascular necrosis in patients receiving chemotherapy for testicular cancer we invited 103 consecutive patients treated by chemotherapy to attend for MRI scan of the hips. Four of 47 (9% (CI 2–20%)) patients scanned and 4/103 (3.8% (CI 1–10%)) of patients invited to participate in the study had evidence of avascular necrosis. As not all patients in the study had completed the at risk period this equates to a 3-year actuarial risk of 6.3% (95% confidence limits (CI) 2.4–16.1). These data suggest that avascular necrosis is an uncommon but significant complication of chemotherapy including steroids as anti-emetics. © 2001 Cancer Research Campaign http://www.bjcancer.com

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Change history

  • 16 November 2011

    This paper was modified 12 months after initial publication to switch to Creative Commons licence terms, as noted at publication

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Author information

Author notes
  1. A M Cook

    Present address: Staffordshire Centre, North Staffordshire NHS Trust, Royal Infirmary, Princess Road, Hartshill, Stoke-on-Trent, Staffordshire, ST4 7LN, UK

  2. A R Padhani

    Present address: Mount Vernon Hospital, Rickmansworth Road, Northwood, Middlesex, HA6 RN, UK

Authors and Affiliations

  1. Academic Department of Radiotherapy and Oncology, Sutton, SM2 5PT, Surrey, UK

    A M Cook & R A Huddart

  2. Department of X-Ray, Sutton, SM2 5PT, Surrey, UK

    A S K Dzik-Jurasz & A R Padhani

  3. Department of Computing and Information, The Royal Marsden NHS Trust, and Institute of Cancer Research, Downs Road, Sutton, SM2 5PT, Surrey, UK

    A Norman

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  2. A S K Dzik-Jurasz
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  5. R A Huddart
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From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

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Cook, A., Dzik-Jurasz, A., Padhani, A. et al. The prevalence of avascular necrosis in patients treated with chemotherapy for testicular tumours. Br J Cancer 85, 1624–1626 (2001). https://doi.org/10.1054/bjoc.2001.2155

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  • Received: 12 March 2001

  • Revised: 02 August 2001

  • Accepted: 18 September 2001

  • Published: 27 November 2001

  • Issue date: 01 December 2001

  • DOI: https://doi.org/10.1054/bjoc.2001.2155

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Keywords

  • testicular cancer
  • avascular necrosis
  • chemotherapy steroids

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