Figure 1
From: Novel biomaterial strategies for controlled growth factor delivery for biomedical applications

The direct approaches for the immobilization/encapsulation of growth factors (GFs) to biomaterials. (a) Physical immobilization techniques. (b) Nonselective covalent immobilization of GFs through their functional residues. (c) Extracellular matrix (ECM)-inspired immobilization reactions used for the orientation of GFs on the surfaces of biomaterials.