Figure 6
From: Novel biomaterial strategies for controlled growth factor delivery for biomedical applications
Polydopamine NPs functionalized on porous scaffolds for BMP-2 immobilization and enhanced bone tissue regeneration. (a) Porous TCP scaffolds; (b) polydopamine NPs immobilized on scaffolds; (c) BMP-2 adsorption on polydopamine NP-modified scaffolds (polydopamine-NP-TCP); (d) In vitro cell culture on porous scaffolds; (e) Attachment and spreading of BMSCs on polydopamine-NP-TCP scaffolds after 1 day; (f) Hematoxylin and eosin (H&E) staining micrographs of polydopamine-NP-TCP scaffolds retrieved after 12-week implantation; (g) Immunohistochemical staining for collagen type I on deparaffinized sections of polydopamine-NP-TCP scaffolds retrieved after 12-week implantation. m, material; nb, new bone; v, vessel.
