Abstract
Maternal-fetal fluid balance is critical during pregnancy, and amniotic fluid is essential for fetal growth and development. The placenta plays a key role in a successful pregnancy as the interface between the mother and her fetus. Aquaporins (AQPs) form specific water channels that allow the rapid transcellular movement of water in response to osmotic/hydrostatic pressure gradients. AQPs expression in the placenta and fetal membranes may play important roles in the maternal-fetal fluid balance.
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Acknowledgements
This study was supported by the National Natural Science Foundation of China (30471828 and 30973206) and the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry [2005]383.
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Sha, Xy., Xiong, Zf., Liu, Hs. et al. Maternal-fetal fluid balance and aquaporins: from molecule to physiology. Acta Pharmacol Sin 32, 716–720 (2011). https://doi.org/10.1038/aps.2011.59
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DOI: https://doi.org/10.1038/aps.2011.59
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