Figure 2
Effects of gelsemine on mechanical threshold and thermal latency. A time course of the effects of gelsemine (4 mg/kg) on mechanical allodynia (A) and thermal hyperalgesia (B) in sham and PSNL mice. Dose-response effects of gelsemine on mechanical threshold (C) and thermal latency (D) in PSNL mice. Pregabalin was used as a reference drug. Data are expressed as mean±SEM (n=7–8). bP<0.05, cP<0.01 vs vehicle-treated PSNL mice. fP<0.01 indicates significant differences among doses of gelsemine.
