Table 2 PN before and after treatment with bortezomib

From: Phytohemagglutinin-induced IL2 mRNA in whole blood can predict bortezomib-induced peripheral neuropathy for multiple myeloma patients

Baseline grade a

Grade after treatment

n (%)

No. of patients with painful PN

n (%)

0

0

27 (44%)

 

58 (95%)

 

1

18 (30%)

1

 
 

2

9 (15%)

8

 
 

3

4 (7%)

3

 

1

1

0 (0%)

 

2 (3%)

 

2

2 (3%)

0

 
 

3

0 (0%)

  

2

2

1 (2%)

0

1 (2%)

 

3

0 (0%)

  

3

3

0 (0%)

  

Total

 

61b

 

61b

  1. Abbreviation: PN, peripheral neuropathy.
  2. One patient died early of disease progression, another lost consciousness and the third received additional chemotherapy.
  3. aGrade was evaluated according to National Cancer Institute Common Terminology Criteria for Adverse Events version 4.0.
  4. bThree patients who were not assessable for toxicity were excluded.
Back to article page