Abstract
Adult mice of strains C3Hf and XVII/G received 2, 4, 5-T by continuous oral administration (80 ppm in the diet). The 2, 4, 5-T preparation contained less than 0-05 ppm of dioxins. In 2, 4, 5-T -treated C3Hf mice a significant increase in the incidence of neoplastic lesions was found. No significant difference was found in the XVII/G strain between the treated and control mice. Rare forms of tumours, which were not observed in the controls, were present in the 2, 4, 5-t -treated C3Hf mice.
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Muranyi-Kovacs, I., Rudali, G. & Imbert, J. Bioassay of 2, 4, 5-trichlorophenoxyacetic acid for carcinogenicity in mice. Br J Cancer 33, 626–633 (1976). https://doi.org/10.1038/bjc.1976.100
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DOI: https://doi.org/10.1038/bjc.1976.100
