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Mechanisms of leucocyte migration inhibition by breast tumour cell fractions

Abstract

Leucocyte migration inhibition by autologous breast tumour cell fractions was mediated by a soluble factor synthesized and released by mononuclear leucocytes and active against migrating granulocytes. This mechanism is similar to that previously described in respect to cell-mediated sensitivity to microbial antigens. Alternative mechanisms involving directly reactive granulocytes or cytophilic antibodies were rarely operative in the migration tests.

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Jones, B. Mechanisms of leucocyte migration inhibition by breast tumour cell fractions. Br J Cancer 34, 14–19 (1976). https://doi.org/10.1038/bjc.1976.115

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  • DOI: https://doi.org/10.1038/bjc.1976.115

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