Figure 1
From: TYRP1 mRNA expression in melanoma metastases correlates with clinical outcome
The TYRP1 mRNA expression and survival of 89 patients with melanoma skin metastases. The distant metastasis-free survival and the overall survival curves (Kaplan–Meier analysis) were determined for patients of the validation population. Patients were distributed according to the TYRP1 mRNA levels (real-time PCR determination) as defined in the ‘Results’. Cox regressions were calculated to determine P-values, hazard ratios (HRs) and 95% confidence intervals (CIs). The symbol ‘+’ indicates the patients who were alive at the time of analysis. The mRNA expression of TYRP1 had a positive predictive value of 94% (P=0.01, Fisher's exact test) for a shorter DMFS (<7.5 years) and a positive predictive value of 96% (P<0.001) for a shorter OS (<15 years).
