Table 2 Relative risk for lung cancer by selected characteristics at reference datea

From: Lung cancer in the Swiss HIV Cohort Study: role of smoking, immunodeficiency and pulmonary infection

 

Lung cancer

Controls

  
 

N

%

N

%

OR b (95% CI)

Smoking-adjusted OR c (95% CI)

Overall

68

 

337

   

Smoking status

 Never

2

3.8

71

27.1

1

 

 Former

6

11.5

63

24.0

3.22 (0.63–16.6)

 

 Current

44

84.6

128

48.9

14.4 (3.36–62.1)

 

 Unknown

16

 

75

   

Pack-yearsd

      

<30

16

36.4

62

50.8

11.5 (2.42–54.6)

 

⩾30

28

63.6

60

49.2

15.9 (3.67–69.1)

 

Unknown

0

 

6

   

History of cART use

 Never

18

26.5

77

22.8

1

1

 Ever

50

73.5

260

77.2

0.67 (0.29–1.52)

0.73 (0.31–1.70)

History of AIDS-defining disease

 No

54

79.4

229

68.0

1

1

 Yes, without pulmonary diseasee

8

11.8

62

18.4

0.53 (0.24–1.18)

0.60 (0.27–1.36)

 Yes, with pulmonary diseasee

6

8.8

46

13.6

0.49 (0.19–1.28)

0.62 (0.22–1.72)

Nadir CD4+ cell count, cells per μl

 ⩾200

31

45.6

142

42.4

1

1

 50–199

26

38.2

124

37.0

0.96 (0.54–1.71)

1.07 (0.57–2.02)

 <50

11

16.2

69

20.6

0.73 (0.34–1.55)

0.87 (0.39–1.90)

 Unknown

0

 

2

   
  1. Abbreviations: cART=combined antiretroviral therapy; CI=confidence interval; OR=odds ratio.
  2. aSee the ‘Materials and Methods’ section for definition of reference date.
  3. bConditioned upon matching variables.
  4. cConditioned upon matching variables and adjusted for smoking status (never/former, current with <30 pack-years, current with ⩾30 pack-years, unknown).
  5. dCurrent smokers only.
  6. eIncludes recurrent bacterial pneumonia, pulmonary tuberculosis, or Pneumocystis carinii pneumonia.
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