Table 1 Characteristics of patients with invasive breast cancer according to CD151 expression
From: Clinical significance of CD151 overexpression in subtypes of invasive breast cancer
CD151 expression | |||||||
|---|---|---|---|---|---|---|---|
Number of patients | Low | High | |||||
Characteristic | n =886 | (%) | n =759 (85.7%) | (%) | n =127 (14.3%) | (%) | P- value |
Age at diagnosis (years) | |||||||
 ⩽ 35 | 33 | 3.7 | 30 | 90.9 | 3 | 9.1 | 0.61 |
 >35 | 853 | 96.3 | 729 | 85.5 | 124 | 14.5 | |
Tumour size | <0.001 | ||||||
 T1 | 363 | 41.0 | 330 | 90.9 | 33 | 9.1 | |
 T2 | 462 | 52.1 | 384 | 83.1 | 78 | 16.9 | |
 T3 | 61 | 6.9 | 45 | 73.8 | 16 | 26.2 | |
Lymph node involvement | <0.001 | ||||||
 N0 | 469 | 52.9 | 420 | 89.6 | 49 | 10.4 | |
 N1 | 228 | 25.7 | 195 | 85.5 | 33 | 14.5 | |
 N2 | 109 | 12.3 | 79 | 72.5 | 30 | 27.5 | |
 N3 | 80 | 9.0 | 65 | 81.3 | 15 | 18.8 | |
AJCC stage | <0.001 | ||||||
 I | 237 | 26.7 | 222 | 93.7 | 15 | 6.33 | |
 II | 444 | 50.1 | 379 | 85.4 | 65 | 14.6 | |
 III | 205 | 23.1 | 158 | 77.1 | 47 | 22.9 | |
Oestrogen receptor | <0.001 | ||||||
 Negative | 342 | 38.6 | 272 | 79.5 | 70 | 20.5 | |
 Positive | 544 | 61.4 | 487 | 89.5 | 57 | 10.5 | |
Progesterone receptor | 0.009 | ||||||
 Negative | 485 | 54.7 | 402 | 82.9 | 83 | 17.1 | |
 Positive | 401 | 45.3 | 357 | 89.0 | 44 | 11.0 | |
HER2 | <0.001 | ||||||
 Negative | 667 | 75.3 | 588 | 88.2 | 79 | 11.8 | |
 Positive | 219 | 24.7 | 171 | 78.1 | 48 | 21.9 | |
Pathological type | 0.275 | ||||||
 Ductal | 812 | 91.6 | 691 | 85.1 | 121 | 14.9 | |
 Lobular | 25 | 2.8 | 22 | 88.0 | 3 | 12.0 | |
 Others | 49 | 5.5 | 46 | 93.9 | 3 | 6.12 | |
Breast cancer subtype | <0.001 | ||||||
 Luminal A | 451 | 50.9 | 407 | 90.2 | 44 | 9.8 | |
 Luminal B | 113 | 12.8 | 94 | 83.1 | 19 | 16.8 | |
 HER2 | 106 | 12.0 | 77 | 72.6 | 29 | 27.4 | |
 TNBC | 216 | 24.4 | 181 | 83.8 | 35 | 16.2 | |
BLBC | 135 | 15.2 | 113 | 83.8 | 22 | 16.2 | |
QNBC | 81 | 9.1 | 68 | 84.0 | 13 | 16.0 | |
CK5/6 | 0.274 | ||||||
 Negative | 760 | 85.8 | 655 | 86.2 | 105 | 13.8 | |
 Positive | 126 | 14.2 | 104 | 82.5 | 22 | 17.5 | |
EGFR | 0.336 | ||||||
 Negative | 762 | 86.0 | 649 | 85.2 | 113 | 14.8 | |
 Positive | 124 | 14.0 | 110 | 88.7 | 14 | 11.3 | |
Adjuvant Chemotherapy | 0.409 | ||||||
 No | 148 | 16.7 | 130 | 87.8 | 18 | 12.2 | |
 Chemotherapy | 738 | 83.3 | 629 | 85.2 | 109 | 14.8 | |
